PancrePlus Rx
Starting At
$59.77
PancrePlus Rx
$59.77
Or save an extra 5% on your first order (up to $20) with Autoship*
$56.79
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Guaranteed lowest authorized price. Learn more.
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Guaranteed lowest authorized price. Learn more.
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Guaranteed lowest authorized price. Learn more.
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Guaranteed lowest authorized price. Learn more.
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Guaranteed lowest authorized price. Learn more.
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Usually ships the same weekday before 3pm CT with veterinary approval.
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Requires veterinary authorization.
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Your pet's veterinarian will provide directions for use.
What is PancrePlus for Dogs and Cats?
- PancrePlus relieves the symptoms of Pancreatic Insufficiency Disorder (PID) in dogs and cats. PID is also known as EPI, or Exocrine Pancreatic Insufficiency.
- This prescription medication replaces the pancreatic enzymes that your dog or cat doesn’t produce but needs to digest the protein, sugar, and fat in food.
- PancrePlus is also fortified with Vitamins, A, D and E to boost your pet’s health.
Why do cats and dogs use PancrePlus?
- Dogs and cats with maldigestion, or Pancreatic Insufficiency Disorder (PID)/ Exocrine Pancreatic Insufficiency (EPI), suffer from weight loss, discomfort, and hair loss because they can’t properly digest the nutrients in food.
- The condition shuts down the pancreas, which produces digestive enzymes.
- PancrePlus replaces those enzymes so that your pet can digest needed proteins, sugars, and fats from food.
What else should I know about PancrePlus?
- Improves digestion and nutrition absorption in pets with PID/ EPI.
- Fast acting.
- Powder form mixes easily with food.
- Pancreatic enzymes made from a pork product.
- Vitamins A, D, and E for extra nutrition.
What problems could my dog or cat have with PancrePlus?
- Cats often do not like the taste of the pancreatic enzymes powder and may be more likely to take tablets or capsules made from crushed tablets. Some cats also may eat one brand of enzymes and not another. Talk to your veterinarian if you are havign trouble with medicating your cat.
How do you use PancrePlus?
- PancrePlus works best when mixed with food and food is allowed to sit before feeding. Always follow your veterinarian's directions for use.
- If using tablets, make sure that your cat or dog gets water or food right after taking the tablets. This may reduce the risk of damage to the esophagous.
- Avoid inhaling powder as it may cause lung irritation or worsen asthma.
- Avoid contacting your skin with the powder. Wash any powder from your skin as soon as possible.
What is in PancrePlus?
- PancrePlus contains pancreatic enzymes that break down the nutrients in food.
- These enzymes typically come from pork sources.
Will I get what I see in the picture?
- PancrePlus is a brand name. You will receive the exact brand that you request.
Is it important for my dog or cat to finish all of the PancrePlus?
- Dogs and cats may use PancrePlus for different lengths of time. Please consult your veterinarian if you have any questions.
Review Summary
46 total reviews
Rated 4.91 out of 5 stars
100% of respondents would recommend this to a friend
Ratings Distribution
42 5 star reviews
4 4 star reviews
0 3 star reviews
0 2 star reviews
0 1 star reviews
Reviews
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My pet is on this medication indefinately
From UndisclosedComments about PancrePlus Tablets, Bottle of 100I purchased this product from VetRx because my dogs vet was out of stock. The amazing thing...so much more affordable! I will continue to use VetRX -
My Girl Maui is Thriving
From UndisclosedComments about PancrePlus Tablets, Bottle of 100My gorgeous German Shepherd Maui was diagnosed with EPI at 10 months old. She had diarrhea and lost 14 pounds - went from 76 down to 62. I was terrified. She is now 16.5 months and back up to 80 lbs where I will keep her because she is truly beautiful. She was doing great with powdered enzyme for a while but then refused to eat. I think she started to hate the taste and the smell. We researched and asked questions and decided to give the tablets a try. We ordered the bottle of 100. She's doing beautifully again! We just put three or four tablets in her meals and let her go. She eats with no hesitation and finishes her entire meal. I just ordered the 500 bottle. Easy, works, she's wonderful so good choice.-
![My Girl Maui is Thriving]()
Maui was diagnosed with EPI at 10 months and is now happy and healthy at 16 1/2 months.
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This medication helps my pet
From UndisclosedComments about PancrePlus Tablets, Bottle of 500My Bella needs to be on this pancreas supplement for the rest of her life. Finding this website and buying in bulk does help save some money -
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Medication saved Jesse's life!
From UndisclosedComments about PancrePlus Powder, 12oz BottleWe are so grateful for Pancre plus. Lifesaving product for Jesse. -
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Lifesaving product for my pup.
From UndisclosedComments about PancrePlus Powder, 8oz BottleJesse needs this medication to live his daily life I am so appreciative to be able to find it order it and receive it. VetRXDirect staff are always helpful and patient when I have needed help. Awesome product great customer service. thank you! -
This medicine saved my dog's life
From Stillwater, MNComments about PancrePlusWhen my lab/shepherd mix Daisy was around a year old, she suddenly started losing weight. It took multiple vet visits (and her weight dropped down to 28 pounds!) to finally figure out she had a condition called Exocrine Pancreatic Insufficiency (EPI). This means that her pancreas doesn't produce the digestive enzymes needed so she can properly digest her food. We initially tried the tablet version of this medicine, but it didn't work for her. We transitioned to this version, which is a powder. We put it on her food with a little water and let it sit for about 10 minutes before she eats. This did the trick! She's 4 years old now and healthy and active as can be. I am so thankful that this medicine exists. Without it, she wouldn't be here and we would be lost without her!-
![This medicine saved my dog's life]()
Daisy
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Great product
From UndisclosedComments about PancrePlus Powder, 8oz BottleMy baby Sugar has EPI and needs these enzymes for life. The people at VET RX Direct always help to get her what she needs on time every time-
![Great product]()
Sugar loves a boat ride -
![Great product]()
Sugar
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I buy this product and only this one for my dogs needs
From UndisclosedComments about PancrePlusIt saves myndogs life while other brands did little to help -
I have to buy this med to keep my dog alive!
From UndisclosedComments about PancrePlusMy little Westie nearly died of IMHA which damage her pancreas. This medicine keeps her body from bruising and stops internal bleeding. I don't know anymore than that about the med. The hospital vet doctor told us that she would have to be on the med for the rest of her life. -
EPI - works great
From UndisclosedComments about PancrePlusMy Sheltie was diagnosed with EPI 4 years ago and she's been on PancrePlus ever since. It's a great product, although a little pricey.
Displaying Reviews 11 - 20
Q & A
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Is there any question for which you do not simply cut & paste from the label??
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How long after giving a dose does the Pancreplus work for ? If given a dose and eating, then going back to eat more 1/2 hour later, would the enzymes still be effective??
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The manufacturer states that the enzymes in PancrePlus begin to digest the food substrate upon contact. The manufacturer also has no timing recommendations in relation to the meal, but they do advise that the tablet should be given before each meal. If your cat or dog is taking the tablet formulation, be certain they get plenty of water or some food right after dosing to reduce the risk for esophageal damage. The powder formulation is mixed into moistened food and left at room temperature for 15-20 minutes before giving to your cat or dog. For best administration advice, it is recommended that you speak with your veterinarian.
Verified Answer
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If I refrigerate the food once it's been broken down by the enzymes, and give it to my dog the next day, is it still just as effective??
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According to the manufacturer’s directions, PancrePlus is added to moistened food (canned or dry). Thorough mixing is necessary to bring the enzymes into close contact with the food particles. After mixing, let stand at room temperature for 15-20 minutes before feeding. The manufacturer states that the enzymes in PancrePlus begin to digest the food substrate upon contact, so there are no product performance issues with placing food in the fridge as long as food spoilage does not occur.
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How long before feeding should we administer the tablets in cats? 10 minutes? 30 minutes? I know it said the powder should sit in food for 15 mins...?
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PancrePlus tablets contain enzymes that help your cat digest and absorb fats, proteins, and carbohydrates. For the tablet formulation, the manufacturer has no timing recommendations in relation to the meal, but they do affirm that it should be given before each meal. If your cat is taking the tablet formulation, be certain they get plenty of water or some food right after dosing to reduce the risk for esophageal damage. For best administration advice, it is recommended that you speak with your veterinarian.
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Have been giving my dog PancrePlus Powder for several years. Is each tablet equal to a teaspoon ??
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According to the product labeling, one tablet of PancrePlus contains 9,000 units of lipase, 57,000 units of protease, and 64,000 units of amylase. One teaspoon of the PancrePlus powder contains 71,400 units of lipase, 388,000 units of protease, and 460,000 units of amylase. This means that one teaspoon of powder contains more lipase, protease, and amylase than one tablet. Please speak to your veterinarian in regards to what dose of PancrePlus is best for your dog.
Verified Answer
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Does this come with a scoop and if so what is the dosage size of the scoop??
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According to the manufacturer, the bottled powder does not come with a scoop. The average dose per meal for dogs is ¾ ~ 1 teaspoon, for cats is ¼ ~ ¾ teaspoon. Speak to your veterinarian to determine the dose required for your pet to achieve the best outcomes.
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Yes it does come with a scoop that measures 1/4 tsp.
Community Answer
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How large are the tablets? I will need them for my cat. She won't eat the powder mixed with her food.?
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PancrePlus Tablets are just under ½ inch in diameter. Please see attached image.
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Are the tablets chewable or need to be swallowed whole??
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According to Plumb’s Veterinary Drug Handbook, PancrePlus tablets should be swallowed whole or crushed then mixed in food. When administering tablets, give food or water immediately following the dose. If using crushed tablets mixed in food, make sure the powder has been moistened prior to administration. Please consult with your veterinarian before administering this medication and follow their specific instructions for use.
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Since my Newfiedoodle has been taking this powder she has a really unpleasant odor around her face. Is this normal?
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Halitosis, or foul smelling breath is not a common side effect associated with administering pancreatic enzyme supplements. Speak with your veterinarian for further assistance as they may want to rule out the most likely reasons and/or offer suggestions on possible different methods of administering pancreatic enzyme supplements.
Verified Answer
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After I put the powder into the food Do I need to add water to mix it??
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According to the manufacturer’s directions for use, PancrePlus should be added to moistened food (canned or dry). Thorough mixing is necessary to bring the enzymes into close contact with the food particles. After mixing, let stand at room temperature for 15-20 minutes.
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Displaying Questions 1 - 10